273.1K
XNAS Volume
High vol.+loss this week
XNAS 01 Apr, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 90,000 | 90,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 50,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 50,000 | 50,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 38,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 38,000 | 38,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 36,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 36,000 | 36,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 28,708 | 0 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 28,708 | 28,708 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 36,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 36,000 | 36,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 90,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 24,000 | 24,000 | - | - | Director Stock Option (right to buy) | |
| Martha J. Demski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 24,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 20,770 | 20,770 | - | - | Director Stock Option (right to buy) | |
| Martha J. Demski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 20,770 | 0 | - | - | Director Stock Option (right to buy) | |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 20,000 | 20,000 | - | - | Director Stock Option (right to buy) | |
| Martha J. Demski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 20,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 12,000 | 12,000 | - | - | Director Stock Option (right to buy) | |
| Martha J. Demski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 12,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 12,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 20,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 20,000 | 20,000 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 20,770 | 0 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 20,770 | 20,770 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 24,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 24,000 | 24,000 | - | - | Director Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 12,000 | 12,000 | - | - | Director Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 100,110 | 100,110 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 60,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 60,000 | 60,000 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 44,352 | 0 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 44,352 | 44,352 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 410,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 410,000 | 410,000 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 325,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 325,000 | 325,000 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 245,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 245,000 | 245,000 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 100,110 | 0 | - | - | Employee Stock Option (right to buy) | |
| Bala S. Manian | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 20,634 | 0 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 12,000 | 12,000 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 12,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 24,000 | 24,000 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 24,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 20,634 | 20,634 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 20,770 | 20,770 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 20,770 | 0 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 20,000 | 20,000 | - | - | Director Stock Option (right to buy) | |
| Bala S. Manian | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 20,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Barbara Troupin | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 40,000 | 0 | - | - | Director Stock Option (right to buy) | |
| Barbara Troupin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 40,000 | 40,000 | - | - | Director Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 125,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 175,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 90,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 90,000 | 90,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 70,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 70,000 | 70,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 42,534 | 42,534 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 42,534 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 125,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 175,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 90,000 | 90,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 90,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 52,500 | 52,500 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 52,500 | 0 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 75,000 | 75,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 125,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 175,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 35,695 | 35,695 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 35,695 | 0 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 41,666 | 41,666 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 41,666 | 0 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 75,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 40,000 | 40,000 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 60,000 | 60,000 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 60,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 40,000 | 40,000 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 40,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 45,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 45,000 | 45,000 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 65,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 65,000 | 65,000 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 14 Feb 2025 | 40,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2025 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 23 Jan 2025 | 10,000 | 37,720 (0%) | 0% | 0.7 | 6,500 | Common Stock |
| Daniel M. Bradbury | Director, EXECUTIVE CHAIRMAN, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 50,000 | 50,000 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 410,000 | 410,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.54 per share. | 02 Jan 2025 | 15,000 | 88,913 (0%) | 0% | 0.5 | 8,100 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Penny Tom | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Peter Colabuono | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Dec 2024 | 40,000 | 40,000 | - | - | Director Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.70 per share. | 14 Nov 2024 | 10,000 | 47,720 (0%) | 0% | 0.7 | 7,000 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Sale of securities on an exchange or to another person at price $ 1.25 per share. | 28 Oct 2024 | 15,000 | 135,246 (0%) | 0% | 1.3 | 18,750 | Common Stock |
| Penny Tom | Principal Accounting Officer | Sale of securities on an exchange or to another person at price $ 1.25 per share. | 25 Oct 2024 | 683 | 9,368 (0%) | 0% | 1.3 | 854 | Common Stock |
| Penny Tom | Principal Accounting Officer | Sale of securities on an exchange or to another person at price $ 1.25 per share. | 25 Oct 2024 | 2,835 | 6,533 (0%) | 0% | 1.3 | 3,544 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.81 per share. | 26 Sep 2024 | 10,000 | 57,720 (0%) | 0% | 0.8 | 8,100 | Common Stock |
| Penny Tom | Principal Accounting Officer | Sale of securities on an exchange or to another person at price $ 0.85 per share. | 16 Sep 2024 | 38,806 | 10,051 (0%) | 0% | 0.8 | 32,985 | Common Stock |
| A. Keyes Jason | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.87 per share. | 16 Jul 2024 | 10,000 | 67,720 (0%) | 0% | 0.9 | 8,700 | Common Stock |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2024 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2024 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2024 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Barbara Troupin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2024 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Charles McDermott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2024 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Yu Xu | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2024 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Connelly Stephen | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Steel D. Bruce | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 410,000 | 410,000 | - | - | Employee Stock Option (right to buy) | |
| Rothman Joel | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Zedelmayer Christine | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| A. Jason Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.58 per share. | 02 Jan 2024 | 8,804 | 135,246 (0%) | 0% | 0.6 | 5,106 | Common Stock |
| A. Keyes Jason | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.58 per share. | 02 Jan 2024 | 8,805 | 58,913 (0%) | 0% | 0.6 | 5,107 | Common Stock |
| Zedelmayer Christine | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.56 per share. | 02 Jan 2024 | 15,000 | 126,442 (0%) | 0% | 0.6 | 8,400 | Common Stock |
| Joel Rothman | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.56 per share. | 02 Jan 2024 | 15,000 | 49,346 (0%) | 0% | 0.6 | 8,400 | Common Stock |
| M. Bradbury Daniel | Director, Executive Chairman, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 50,000 | 50,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.56 per share. | 02 Jan 2024 | 15,000 | 50,108 (0%) | 0% | 0.6 | 8,400 | Common Stock |
| Rothman Joel | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.58 per share. | 02 Jan 2024 | 8,804 | 58,150 (0%) | 0% | 0.6 | 5,106 | Common Stock |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2023 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2023 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2023 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Barbara Troupin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2023 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Charles McDermott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2023 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Yu Xu | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2023 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, Executive Chairman, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 50,000 | 50,000 | - | - | Employee Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 410,000 | 410,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 1.19 per share. | 03 Jan 2023 | 4,444 | 35,108 (0%) | 0% | 1.2 | 5,288 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 1.85 per share. | 03 Jan 2023 | 9,033 | 111,442 (0%) | 0% | 1.8 | 16,711 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Joel Rothman | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Joel Rothman | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 1.19 per share. | 03 Jan 2023 | 3,821 | 34,346 (0%) | 0% | 1.2 | 4,547 | Common Stock |
| Joel Rothman | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 1.85 per share. | 03 Jan 2023 | 6,244 | 30,525 (0%) | 0% | 1.8 | 11,551 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.83 per share. | 29 Aug 2022 | 7,000 | 77,720 (0%) | 0% | 2.8 | 19,810 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.52 per share. | 06 Jun 2022 | 5,000 | 84,720 (0%) | 0% | 2.5 | 12,600 | Common Stock |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Charles McDermott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Yu Xu | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.18 per share. | 04 Apr 2022 | 8,000 | 89,720 (0%) | 0% | 3.2 | 25,440 | Common Stock |
| Daniel M. Bradbury | Director, Executive Chairman, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 38,000 | 38,000 | - | - | Employee Stock Option (right to buy) | |
| Barbara Troupin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 325,000 | 325,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Joel Rothman | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 2.35 per share. | 10 Dec 2021 | 5,585 | 23,296 (0%) | 0% | 2.4 | 13,125 | Common Stock |
| Joel Rothman | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 2.35 per share. | 10 Dec 2021 | 1,290 | 24,281 (0%) | 0% | 2.4 | 3,032 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.08 per share. | 01 Dec 2021 | 5,000 | 97,720 (0%) | 0% | 5.1 | 25,402 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.45 per share. | 16 Nov 2021 | 15,000 | 109,759 (0%) | 0% | 2.5 | 36,750 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2021 | 15,000 | 75,000 | - | - | Employee Stock Option | |
| Christine Zedelmayer | Sr. Vice President and COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2021 | 8,334 | 41,666 | - | - | Employee Stock Option | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 16 Nov 2021 | 4,084 | 94,759 (0%) | 0% | 5.5 | 22,401 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.45 per share. | 16 Nov 2021 | 8,334 | 98,843 (0%) | 0% | 2.4 | 20,418 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 16 Nov 2021 | 7,350 | 102,409 (0%) | 0% | 5.5 | 40,315 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.01 per share. | 06 Oct 2021 | 5,625 | 993,000 (5%) | 0% | 7.0 | 39,418 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Oct 2021 | 2,467 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Oct 2021 | 5,625 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.01 per share. | 06 Oct 2021 | 2,467 | 993,000 (5%) | 0% | 7.0 | 17,288 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.80 per share. | 06 Oct 2021 | 2,467 | 995,467 (5%) | 0% | 2.8 | 6,908 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.75 per share. | 06 Oct 2021 | 5,625 | 998,625 (5%) | 0% | 4.8 | 26,719 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.74 per share. | 27 Sep 2021 | 8,000 | 102,720 (0%) | 0% | 6.7 | 53,924 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.72 per share. | 27 Jul 2021 | 5,000 | 110,720 (0%) | 0% | 5.7 | 28,585 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 2.35 per share. | 10 Jun 2021 | 5,535 | 17,711 (0%) | 0% | 2.3 | 13,007 | Common stock, par value $0.0001 per share |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 2.35 per share. | 10 Jun 2021 | 9,032 | 90,509 (0%) | 0% | 2.3 | 21,225 | Common stock, par value $0.0001 per share |
| Joel Rothman | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 2.35 per share. | 10 Jun 2021 | 7,742 | 22,991 (0%) | 0% | 2.4 | 18,194 | Common stock, par value $0.0001 per share |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.18 per share. | 04 Jun 2021 | 10,495 | 993,000 (5%) | 0% | 7.2 | 75,315 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.80 per share. | 04 Jun 2021 | 6,509 | 999,509 (5%) | 0% | 2.8 | 18,225 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.01 per share. | 04 Jun 2021 | 6,509 | 993,000 (5%) | 0% | 7.0 | 45,601 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.75 per share. | 04 Jun 2021 | 7,030 | 1,000,030 (5%) | 0% | 4.8 | 33,393 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.00 per share. | 04 Jun 2021 | 7,030 | 993,000 (5%) | 0% | 7.0 | 49,245 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.80 per share. | 04 Jun 2021 | 8,490 | 1,001,490 (5%) | 0% | 2.8 | 23,772 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.08 per share. | 04 Jun 2021 | 8,490 | 993,000 (5%) | 0% | 7.1 | 60,145 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.75 per share. | 04 Jun 2021 | 13,900 | 1,006,900 (5%) | 0% | 4.8 | 66,025 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.14 per share. | 04 Jun 2021 | 13,900 | 993,000 (5%) | 0% | 7.1 | 99,264 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.75 per share. | 04 Jun 2021 | 10,495 | 1,003,495 (5%) | 0% | 4.7 | 49,851 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2021 | 6,509 | 8,490 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2021 | 7,030 | 24,845 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2021 | 8,490 | 0 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2021 | 13,900 | 10,945 | - | - | Employee Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2021 | 10,945 | 0 | - | - | Employee Stock Option (right to buy) | |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2021 | 20,770 | 20,770 | - | - | Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2021 | 20,770 | 20,770 | - | - | Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2021 | 20,770 | 20,770 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.50 per share. | 26 May 2021 | 5,000 | 115,720 (0%) | 0% | 6.5 | 32,484 | Common Stock |
| Charles McDermott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2021 | 20,770 | 20,770 | - | - | Stock Option (right to buy) | |
| Yu Xu | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Mar 2021 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| Dolca Thomas | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jan 2021 | 450,000 | 450,000 | - | - | Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, Executive Chairman, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 36,000 | 36,000 | - | - | Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 245,000 | 245,000 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 4.52 per share. | 28 Dec 2020 | 25,000 | 993,000 (5%) | 0% | 4.5 | 113,045 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.74 per share. | 23 Dec 2020 | 8,000 | 120,720 (0%) | 0% | 4.7 | 37,914 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Other type of transaction at price $ 2.35 per share. | 10 Dec 2020 | 5,362 | 12,176 (0%) | 0% | 2.4 | 12,601 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Other type of transaction at price $ 2.35 per share. | 10 Dec 2020 | 1,097 | 81,477 (0%) | 0% | 2.4 | 2,578 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 5.62 per share. | 28 Sep 2020 | 25,000 | 1,018,000 (5%) | 0% | 5.6 | 140,395 | Common Stock |
| Stephen Connelly | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 8.13 per share. | 13 Jul 2020 | 250,000 | 1,043,000 (6%) | 1% | 8.1 | 2,033,475 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Other type of transaction at price $ 2.41 per share. | 10 Jun 2020 | 5,014 | 6,814 (0%) | 0% | 2.4 | 12,084 | Common Stock |
| Christine Zedelmayer | Sr. Vice President and COO | Other type of transaction at price $ 2.41 per share. | 10 Jun 2020 | 9,570 | 80,380 (0%) | 0% | 2.4 | 23,064 | Common Stock |
| Daniel M. Bradbury | Director, Executive Chairman, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 28,708 | 28,708 | - | - | Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 100,110 | 100,110 | - | - | Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 20,634 | 20,634 | - | - | Stock Option (right to buy) | |
| Charles McDermott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 19,916 | 19,916 | - | - | Stock Option (right to buy) | |
| Martha J. Demski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2020 | 24,000 | 24,000 | - | - | Stock Option (right to buy) | |
| Mark Pruzanski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2020 | 24,000 | 24,000 | - | - | Stock Option (right to buy) | |
| Bruce D. Steel | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2020 | 60,000 | 60,000 | - | - | Stock Option (right to buy) | |
| Bala S. Manian | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2020 | 24,000 | 24,000 | - | - | Stock Option (right to buy) | |
| Charles McDermott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2020 | 24,000 | 24,000 | - | - | Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2020 | 60,000 | 60,000 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 125,000 | 0 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 208,216 | 0 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 208,216 | 208,216 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 90,000 | 0 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 125,000 | 125,000 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 90,000 | 0 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 70,000 | 70,000 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 70,000 | 0 | - | - | Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 50,000 | 0 | - | - | Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 90,000 | 0 | - | - | Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Apr 2020 | 35,695 | 35,695 | - | - | Stock Option (right to buy) | |
| Christine Zedelmayer | Sr. Vice President and COO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 22 Apr 2020 | 35,695 | 0 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.03 per share. | 18 Feb 2020 | 5,000 | 130,520 (0%) | 0% | 5.0 | 25,138 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.41 per share. | 21 Jan 2020 | 5,000 | 135,520 (0%) | 0% | 4.4 | 22,043 | Common Stock |
| Daniel M. Bradbury | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2019 | 36,000 | 36,000 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2019 | 125,000 | 125,000 | - | - | Stock Option (right to buy) | |
| Bruce D. Steel | Director, President, CBO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2019 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2019 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2019 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.60 per share. | 03 Sep 2019 | 5,000 | 138,720 (0%) | 0% | 3.6 | 17,981 | Common Stock |
| Jason A. Keyes | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.99 per share. | 01 Aug 2019 | 5,000 | 143,720 (0%) | 0% | 4.0 | 19,941 | Common Stock |
| Martha J. Demski | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2019 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Mark Pruzanski | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2019 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Bala S. Manian | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2019 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Charles McDermott | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2019 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2019 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Krishna R. Polu | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2019 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Bruce D. Steel | Director, President, CBO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2019 | 45,648 | 45,648 | - | - | Stock Option (right to buy) | |
| Bruce D. Steel | Director, President, CBO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2019 | 44,352 | 44,352 | - | - | Stock Option (right to buy) | |
| Jason A. Keyes | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2019 | 70,000 | 70,000 | - | - | Stock Option (right to buy) | |
| Stephen Connelly | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2019 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Daniel M. Bradbury | Director, Chief Executive Officer | Other type of transaction at price $ 11.20 per share. | 16 Oct 2018 | 9,699 | 742,399 (4%) | 0% | 11.2 | 108,629 | Common Stock |
| Daniel M. Bradbury | Director, Chief Executive Officer | Other type of transaction at price $ 11.20 per share. | 16 Oct 2018 | 38,796 | 2,969,596 (17%) | 0% | 11.2 | 434,515 | Common Stock |
| Bruce D. Steel | Director, President, CBO | Other type of transaction at price $ 11.20 per share. | 16 Oct 2018 | 48,495 | 48,495 (0%) | 0% | 11.2 | 543,144 | Common Stock |